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Resveratrol

Resveratrol

Resveratrol is a naturally occurring polyphenol, found primarily in the skin and seeds of grapes. In plants, resveratrol functions as part of the defense system against cellular damage and disease, and is synthesized in response to stress, infection, and UV radiation. In recent and ongoing studies, resveratrol has received attention due to its potent antioxidant, anti-inflammatory, anti-cancer, and anti-aging properties. Several studies have demonstrated that resveratrol is an effective antioxidant, and it is thought that because it contains highly hydrophilic and lipophilic properties, it can provide more effective protection than other well-known antioxidants like vitamins C and E. Resveratrol has also been found to boost anti-aging enzymes called sirtuins, which are universal regulators of aging in virtually all living organisms. Sirtuins serve as guardians of the cell, allowing cells to survive damage and delay cell death. Study data suggests that Resveratrol may be a potent regulator of sleep-wake rhythms and could be of major interest in the study of sleep, associated with aging and neuropathology.

SYNONYMS:
Acetyl Resveratrol

REFERENCES:
Pifferi F, Rahman A, Languille S, Auffret A, Babiloni C, Blin O, Lamberty Y, Richardson JC, Aujard F., Effects of dietary resveratrol on the sleep-wake cycle, UMR CNRS-MNHN 7179, Brunoy, France, 2012 Apr;29(3):261-70.

Afaq F, Mukhtar H. Botanical antioxidants in the prevention of photocarcinogenesis and photaging. Exp Dermatol 2006; 15: 678-84.

Labinskyy N, Csiszar A, Veress G, et al. Vascular Dysfunction in Aging: Potential Effects of Resveratrol, an Anti-Inflammatory Phytoestrogen. Curr Med Chem. 2006; 13(9): 989–996.

Markus MA, Morris BJ. Resveratrol in prevention and treatment of common clinical conditions of aging. Clinical Interventions in Aging 2008; 3(2): 331-339.

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